Experimental drug provided to Dallas Ebola patient
North Carolina drugmaker is providing its experimental antiviral drug to a Dallas patient being treated for Ebola, an emergency step authorized by the Food and Drug Administration.
Officials at Texas Health Presbyterian Hospital said Monday that their patient, Thomas Eric Duncan, is in critical condition and being treated with brincidofovir, an oral medicine developed by Chimerix Inc.
The Durham, North Carolina-based drugmaker said earlier that physicians sought FDA permission to use the company’s drug, which is in late-stage testing for several other types of viruses.
The FDA grants emergency access to unapproved drugs on a case-by-case basis, usually when a patient faces a life-threatening condition for which there are no alternatives. The agency has not approved any drugs or vaccines to safely and effectively treat Ebola.
Duncan was diagnosed with Ebola in Dallas last Tuesday after recently arriving from Liberia.
Brincidofovir is an antiviral drug being tested against several common viruses, including one that infects patients undergoing bone marrow transplants. Chimerix is working with the U.S. Department of Defense on developing the drug as a treatment against smallpox.
Laboratory tests suggested it may also work against Ebola.
That’s worth repeating. This is NOT an Ebola drug ~ developed FOR the treatment or prevention of Ebola.
This a drug in development for other things entirely, that someone’s praying may work on Ebola, too.
Because WE GOT NOTHIN’.
EVEN AN OZARKS CORONER GETS SURPLUS MILITARY GUNS
Doug Wortham used a Defense Department giveaway program for law enforcement to stock his office with an assault rifle, a handgun and a Humvee – even though the people in his custody are in no condition to put up a fight.
Wortham is the Sharp County, Arkansas, coroner. He says the Humvee helps him navigate the rugged terrain of the Ozarks foothills, but he struggled to explain why he needs the surplus military weapons he acquired more than two years ago.
“I just wanted to protect myself,” he said.
From the coming ZOMBIE APOCALYPSE the CDC is lying about, too!
I mean, it IS the Ozarks…
For that we give thanks. But now it seems that the potential exists for something a bit messier: she is expected over the next few days to strengthen to a Super Typhoon, i.e. with winds in excess of 150 mph, and potentially threaten Japan.
Oh, and the chance exists of a dead-on strike at Fukushima.
What could possibly go wrong?
God, I really can’t wait for these idiots to be gone
ISTANBUL — Vice President Joe Biden apologized to the United Arab Emirates Sunday for charging that the oil-rich ally had been supporting al Qaida and other jihadi groups in Syria’s internal war, his second apology in as many days to a key participant in the U.S.-led coalition against Islamic State extremists.
…of poetry in motion.
Less mind figure it out to begin with. I hope they’re not giving kids 75 problems for homework anymore, like we used to get. It’d take a week, with all the extra writing.
Common Core = No Common Sense pic.twitter.com/zmD3ma8bR3
— Sherry Lucas (@PorchPhilosophy) October 3, 2014
It’s also starting to look vaguely like the crap that they tried to foist on us in the ’60’s.
OMG, it is so outrageous and criminal that the female head of the Secret Service was forced to resign
Islamic State extremists have herded hundreds of women to be given to its fighters in Syria as a reward or sold as sex slaves and have summarily executed women in professions, according to the United Nations.
About 500 women and girls of the Yezidi and Christian minority communities were given to Islamic State fighters or trafficked for sale in markets in Mosul in Iraq and Raqqa in Syria, according to a report published today by the UN mission in Iraq and the world body’s human-rights office in Geneva.
“Women and girls are brought with price tags for the buyers to choose and negotiate the sale. The buyers were said to be mostly youth from the local communities,” according to the 29-page report, which cites testimony from witnesses and surviving victims. “Apparently ISIL was ‘selling’ these Yezidi women to the youth as a means of inducing them to join their ranks.”
This is what the Unicorn Whisperer considers the JV Team.
Because, if one goes by the wisdom so passionately imparted by his speeches, the real enemy is of course Fox News.
…removed from their website the minor statement that they HAVE NO FRICKIN’ IDEA HOW EBOLA IS TRANSMITTED, they’ve left UP an interim guidance for hospitals which says the little wrigglers can survive (“remain viable”) on surfaces or in pools of goo, for SIX DAYS.
How long does Ebola virus persist in indoor environments?
Only one laboratory study, which was done under environmental conditions that favor virus persistence, has been reported. This study found that under these ideal conditions Ebola virus could remain active for up to six days.1 In a follow up study, Ebola virus was found, relative to other enveloped viruses, to be quite sensitive to inactivation by ultraviolet light and drying; yet sub-populations did persist in organic debris.
2. In the only study to assess contamination of the patient care environment during an outbreak, conducted in an African hospital under “real world conditions”, virus was not detected by either nucleic acid amplification or culture in any of 33 samples collected from sites that were not visibly bloody. Virus was detected on a blood-stained glove and bloody intravenous insertion site by nucleic acid amplification, which may detect non-viable virus, but not by culture for live, infectious virus.3 Based upon these data and what is known regarding the environmental infection control of other enveloped RNA viruses, the expectation is with consistent daily cleaning and disinfection practices in U.S. hospitals that the persistence of Ebola virus in the patient care environment would be short – with 24 hours considered a cautious upper limit.
They also recommend “sanitary sewers” for Ebola patients if they, like, have to use a bathroom. Should be easy enough to come by, eh?
…it turns out that things are a bit more…complicated
Last night’s post was based on the understanding that our dear patient in Dallas didn’t know he was infected, and happened to get exposed as he was making a planned trip to visit family in the United States. That would indicate that it would be a comparatively isolated incident (around twenty people exposed and will be monitored).
That no longer appears to be the case.
More below the fold. I apologize in advance for the length of this, but there’s a lot to talk about…
Okay, so here’s what we know as of this evening…
Our patient’s name appears to be Thomas Eric Duncan of Liberia. Check out Bryan Preston’s brief rundown of the NY Times article.
He came into direct contact with a friend who had Ebola. He rode with her in a taxi and carried her from the taxi to a hospital on September 15, four days before he flew to the United States. She was turned away from the hospital because the Ebola ward was full.
She died of Ebola early the following morning. Her brother also got sick and shows Ebola symptoms. That was at the same time that Duncan started getting sick. He left Liberia and arrived in Texas on September 20. Six days later he sought treatment at Texas Presbyterian Hospital, and was sent home. He returned two days later, and has been confirmed to be infected with Ebola.
Duncan also abruptly quit his job on September 4, so he might have already planned the trip to see his family in the U.S.
But he certainly knew that he had been exposed to Ebola by the time he boarded that plane and came to Texas, four days after his friend died of it. He must surely have known it when he first visited the Texas Presbyterian Hospital, and he must have known it when the doctors sent him home.
Editorial note: it has NOT been established that he was feeling sick prior to getting on the plane, despite the above blockquote.
Let that sink in, though: he knew he’d been exposed, and it’s not unfair to deduce that he thought to himself, “the Americans will save me”.
Read the rest of the article.
It will infuriate and concern you.
But rest assured, our border is secure.
And a lot more need to go in many many agencies
We are run by a bunch of mealy mouthed useless bureaucrats.
Get rid of all of them.
It’s true, it really is.
Further proof (not that you need it) can be found in that my first reaction to reading this was to laugh: In April there was a “Food Safety Summit” in Baltimore that hundreds attended.
And over 200 of them got sick from the chicken they were served for lunch
The pan-seared breast of Chicken Marsala served by the Baltimore Convention Center’s exclusive caterer was the food item most commonly consumed by the 216 attendees sickened by the lunch served last April 9 at the Food Safety Summit’s annual conference. It was likely contaminated with Clostridium perfringens (C. perfringens), a spore-forming gram-positive bacterium commonly found on raw meat and poultry.
Do you drink a glass of wine with dinner every night? That puts you in the top 30 percent of American adults in terms of per-capita alcohol consumption. If you drink two glasses, that would put you in the top 20 percent.
But in order to break into the top 10 percent of American drinkers, you would need to drink more than two bottles of wine with every dinner. And you’d still be below-average among those top 10 percenters.
The top 10 percent of American drinkers – 24 million adults over age 18 – consume, on average, 74 alcoholic drinks per week. That works out to a little more than four-and-a-half 750 ml bottles of Jack Daniels, 18 bottles of wine, or three 24-can cases of beer. In one week.
Or, if you prefer, 10 drinks per day.
Mind you, I could give that a shot on any given day.
But not per day.
…but just can’t be bothered to DO it once it’s yours.
REPORT: OBAMA HAS MISSED OVER HALF HIS SECOND-TERM DAILY INTEL BRIEFINGS
A new Government Accountability Institute (GAI) report reveals that President Barack Obama has attended only 42.1% of his daily intelligence briefings (known officially as the Presidential Daily Brief, or PDB) in the 2,079 days of his presidency through September 29, 2014.
The GAI report also included a breakdown of Obama’s PDB attendance record between terms; he attended 42.4% of his PDBs in his first term and 41.3% in his second.
The GAI’s alarming findings come on the heels of Obama’s 60 Minutes comments on Sunday, wherein the president laid the blame for the Islamic State’s (ISIS) rapid rise squarely at the feet of his Director of National Intelligence James Clapper.
First of all, he’s probably HATIN’ on somebody keeping tabs on him (HOW DARE THEY! He’s the PRESIDENT!!!) Secondly, keeping us safe is boring. Not like a tidy little Par 3 in Martha’s Vineyard, where it’s a thrill a minute.
Third is, God forbid, we GOT hit, he’d get to be a hero on TV. Where he plays President.
I can not believe it.
My Bride’s only 29…how can we possibly have a 21-yr-old???????
And now she’s spreading her wings…
We love you so, Dear Sweet Girl.
The blueberry and ginger flavor in these creamy desserts are a better mix than the sisterly duo in Woody Allen’s dramedy about a crumbling socialite. But the extravagant Jasmine and the blue collar Ginger do have their sweet sides, to be sure. Dish out these mini parfaits as Cate Blanchett and Sallie Hawkins each vie for gold statuettes on Oscar night.??MPE Realisations Limited formerly Land and Marine Project Engineering Limited
At least I think this was spam…
They had some nice fresh new beers on tap:
This is the first pint of their “Leonardville Lager”
Lightly carbonated and very full-bodied for a lager. Tasty.
And for you Oktober Festers they have a “Munchen Dark”
Nice and caramel/chocolaty.
I really like having a brewer in town where you can just hang out with the guys making the beer and shoot the breeze.
…I tip my cap to PETA
BHOPAL: People for the Ethical Treatment of Animals’ (Peta) first shot at religious activism — a call to Muslims to observe a vegetarian Eid this October — has misfired. It met with violent protests here on Monday.
One policeman was injured and a Peta volunteer roughed up by protestors, which included women, and later whisked away by Bhopal police.
Peta woman volunteer “Benazir Suraiya” attempted to make an appeal to Muslims to go vegetarian at the legendary Taj-ul-Masajid, said to be one of Asia’s largest mosques.
Camouflaged in a green hijab, to highlight the importance of vegetarianism, she walked towards the mosque gates with a couple of PETA volunteers holding a placard in Urdu and English which read: “Make Eid Happy for All. Try Vegan”.
It went about as well as you might expect.
But I do give them Big Credibility Points for trying.
Mr. Smart Power Peace Prize goes off to war
(CNN) — The United States and several Arab nations rained bombs on ISIS targets in Syria on Tuesday — the first U.S. military offensive in the war-torn country and a forceful message to the militant group that the U.S. would not stand by idly while it carried out its rampage of terror.
The airstrikes focused on the city of Raqqa, the declared capital of ISIS’ self-proclaimed Islamic State. But other areas were hit as well.
The operation began with a flurry of Tomahawk missiles launched from the sea, followed by attacks from bomber and fighter aircraft, a senior U.S. military official told CNN.
‘There are five Arab nations involved’
The goal: Taking out ISIS’ ability to command, train and resupply its militants.
Evul Schtupid Illegal Bush: Congress Approval? Check. UN Approval? Check.
Unicorn Whisperer Obama: I won.
No love for Mr. Jenn-Jish Khan
To the extent that Kerry, the uncircumcised old geezer, suddenly became an Islamic jurist, issuing a verdict to the people that the Islamic State was distorting Islam, that what it was doing was against Islamic teachings, and that the Islamic State was an enemy of Islam.
I have to admit I chuckled at that.